April 20^th

Opening Remarks & Presentation: Introduction of CLS

——Prof. Yi Rao (CLS/PKU)

Opening Remarks & Presentation：Introduction of iCeMS

——Prof. Norio Nakatsuji (iCeMS)

9:40-9:50

9:50-10:00

Session: Cellular and Molecular Biology (I)

Prof. Ouyang Qi (CLS/PKU)

Reverse Engineering in Synthetic Biology

10:00-10:20

Prof. Yoshie Harada (iCeMS)

Development of a Novel Single-Molecule Imaging Technique Using Fluorescent Diamond Nanoparticles

10:20-10:40

Coffee Break

10:40-11:00

Prof. Liangyi Chen (PKU)

Visualization and Mechanistic Study of Clathrin-dependent Fast Vesicle Recycling in Pancreatic Beta Cells

11:00-11:20

Prof. Kazumitsu Ueda (iCeMS)

Mechanism of function and regulation of ABCA1 in HDL formation

11:20-11:40

Prof. Wanli Liu (THU)

Capturing the Dynamics of B Cell ActivationUsing High Resolution High Speed TIRFM Imaging

11:40-12:00

Lunch

12:00-13:30

Session: Cellular and Molecular Biology (II)

Dr. Peter Carlton (iCeMS)

Chromatin structure visualized with super-resolution microscopy

13:30-13:50

Prof. Yanyi Huang (PKU)

QuantitativelyMeasuretheCellMigration:Blank-FillingonAChip

13:50-14:10

Dr. Takuya Yamamoto (iCeMS/CiRA)

Reversion of somatic splicing during the reprogramming process

14:10-14:30

Prof. Peng Xi (PKU)

λ/10 Resolution CW STED Nanoscopy and Its Application in Cellular Imaging

14:30-14:50

Dr. Dan Ohtan Wang (iCeMS)

Spatial Regulation of Gene Expression in Neurons during Long-term Plasticity

14:50-15:10

Group Photo of All Attendees

15:10-15:20

Coffee Break & Free Discussion

15:20-16:00

MOU Agreement Signing Ceremony

16:00-17:00

Joint Symposium Welcome Reception

17:30-19:30

April 21^st

Session: Nanomedicine, Drug Delivery and Perspectives

Prof. Mitsuru Hashida (iCeMS)

Cell-specific Delivery of Nucleic Acid Drugs with a Combination of Glycosylated Bubble Lipoplexes and Ultrasound Exposure

9:40-10:00

Prof. Xing Chen (PKU)

Carbon Nanotube-Assisted Optical Activation of TGF-signaling

10:00-10:20

Dr. Tatsuya Murakami (iCeMS)

Biochemical Engineering of Mesoscale Lipid-Protein Composite Biomaterials for Drug Delivery System

10:20-10:40

Coffee Break

10:40-11:00

Prof. Weiping Gao (THU)

In Situ, Site-Specific Growth of Stealth Polymers from Proteins forTargeted Drug Delivery

11:00-11:20

Prof. Ying Luo (PKU)

Dendrimer-based Delivery Systems for Small RNA Delivery

11:20-11:40

Lunch

11:40-12:30

Poster Session

12:30-14:00

Session: Mesoscopic Integration of Cell and Material Sciences

Prof. Guoqiang Chen (THU)

Microbial Polyhydroxyalkanotes as Tissue Engineering Materials

14:00-14:20

Prof. Yong Chen (iCeMS)

Development strategy of artificial cellular microenvironments

14:20-14:40

Prof. Zigang Ge (PKU)

Cells Behave Distinctly within Sponges and Hydrogels due to Differences of Internal Structures

14:40-15:00

Coffee Break

15:00-15:20

Prof. Jianzhong Xi (PKU)

Genome-Wide Screen of Functional Genes Regulating Cancer Metastasis

15:20-15:40

Prof. Akihiro Kusumi (iCeMS)

Organizing Principles of the Plasma Membrane:

Three-tiered Hierarchical Meso-scale Domain Architecture

Revealed by Single-molecule Tracking

15:40-16:00

Prof. Delin Kong (Nankai U)

RGD peptide coated poly (epsilon-caprolactone) grafts induced rapid endothelialization in rats and rabbits

16:00-16:20

Prof. Chunyang Xiong (PKU)

Quantitative Investigation Of Cell-Matrix Interactions Using Traction Force Microscopy

16:20-16:40

Prof. Yanan Du （THU）

Micro-engineered biomaterials with bio-mimetic heterogeneity for controlling cell fates

16:40-17:00

Coffee Break &Free Discussion

17:00-17:30

Dinner

17:30-19:30

April 22^nd

Session: Stem Cell Sciences and Technologies

Prof. Norio Nakatsuji (iCeMS)

Chemical Control of Human Pluripotent Stem Cell Differentiation and Creation of Neurodegenerative Disease Model Cells

9:40-10:00

Prof. Fuchou Tang (PKU)

TracingPluripotencyofMammalianEarlyEmbryosand

EmbryonicStemCellsbySingleCellRNA-SeqAnalysis

10:00-10:20

Prof. Kehkooi Kee (THU)

Studying Human Germ Cell Development in Vitro Differentiation of Stem Cells

10:20-10:40

Coffee Break

10:40-11:00

Prof. Hong Kui Deng (CLS/PKU)

Directed Differentiation of Human Pluripotent Stem Cells

11:00-11:20

Prof. Wei Guo (THU)

PTEN, Hematopoietic Stem Cells and Leukemia Stem Cells

11:20-11:40

Prof. Jie Na (THU)

Aurora Kinase B and C Have Distinct Functions in Mouse Oocytes and Preimplantation Embryos

11:40-12:00

Lunch

12:00-12:30

Poster Session

12:30-14:00

Prof. Qin Shen (CLS/THU)

Neural Stem Cells: Lineage and Niche

14:00-14:20

Prof. Motonari Uesugi (iCeMS)

Small Molecule Tools for Cell Biology and Cell Therapy

14:20-14:40

Prof. Xiaohua Shen (THU)

Epigenetic Regulation of Stem Cell Pluripotency and Oncogenesis by Polycomb Group Proteins

14:40-15:00

Prof. Xing Chen (CLS/PKU)

Chemically Probing Glycosylation in Stem Cells

15:00-15:20

Coffee Break

15:20-15:40

Prof. Yasuhiro Yamada (iCeMS/CiRA)

Transient expression of reprogramming factors in vivo results in cancer-like phenotype in mice

15:40-16:00

Prof. Yugang Wang (PKU)

The Intrinsic Dynamic Equilibrium Between Cancer Stem Like Cells and Non-Stem Cancer Cells in Human Cancer Cell Populations

16:00-16:20

Prof. Yangming Wang (PKU)

Micro-Regulators in Embryonic Stem Cells

16:20-16:40

Closing Remarks:

Prof. Yigong Shi (CLS/ THU）& Prof. Norio Nakatsuji (iCeMS)

16:40-17:00

Tsinghua Campus Tour & Dinner

17:00-19:30

End of Joint Symposium