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A single-cell transcriptomic analysis reveals precise pathways and regulatory mechanisms underlying hepatoblast differentiation

Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level

CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair

Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State

Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells

Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing

Sperm cells are passive cargo of the pollen tube in plant fertilization

Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation

Low genetic diversity and strong population structure shaped by anthropogenic habitat fragmentation in a critically endangered primate, Trachypithecus leucocephalus

Single-cell sequencing deciphers a convergent evolution of copy number alterations from primary to circulating tumour cells

Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA

Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers

Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions

Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe

Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells

Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency

The Super Elongation Complex Drives Neural Stem Cell Fate Commitment

Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution

The Arabidopsis RING-Type E3 Ligase TEAR1 Controls Leaf Development by Targeting the TIE1 Transcriptional Repressor for Degradation

Noncanonical role of Arabidopsis COP1/SPA complex in repressing BIN2-mediated PIF3 phosphorylation and degradation in darkness