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Remodeling ceramide homeostasis promotes functional maturation of human pluripotent stem cell-derived β cells

Big cats persisting in human-dominated landscape: Habitat suitability and connectivity of leopards in central North China

From sub-Saharan Africa to China: evolutionary history and adaptation of Drosophila melanogaster revealed by population genomics

Sex differences orchestrated by androgens at single-cell resolution

Arabidopsis transcription factor TCP4 controls the identity of the apical gynoecium

The effect of trisomic chromosomes on spatial genome organization and global transcription in embryonic stem cells

Architecture and activation of human muscle phosphorylase kinase

Monitoring norepinephrine release in vivo using next-generation GRABNE sensors

Modeling viral evolution: A novel SIRSVIDE framework with application to SARS-CoV-2 dynamics

Substrates and drug recognition mechanisms of SLC19A3

Toll/interleukin-1 receptor (TIR) domain-containing proteins have NAD-RNA decapping activity

Fork coupling directs DNA replication elongation and termination

Parental histone transfer caught at the replication fork

Near-cognate tRNAs increase the efficiency and precision of pseudouridine-mediated readthrough of premature termination codons

Improved green and red GRAB sensors for monitoring spatiotemporal serotonin release in vivo

Programmable RNA base editing via targeted modifications

Deep whole-genome analysis of 494 hepatocellular carcinomas

Rice transcriptional repressor OsTIE1 controls anther dehiscence and male sterility by regulating JA biosynthesis

Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing

Molecular Insights into the Adaptive Evolution of SARS-CoV-2 Spike Protein