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A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo

Noncoding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability

Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection

Increasing the efficiency and precision of prime editing with guide RNA pairs

RAG2 abolishes RAG1 aggregation to facilitate V(D)J recombination

T6SS translocates a micropeptide to suppress STING-mediated innate immunity by sequestering manganese

PmiREN2.0: from data annotation to functional exploration of plant microRNAs

Prey partitioning and livestock consumption in the world’s richest large carnivore assemblage

Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes

The genetics and evolution of eye color in domestic pigeons (Columba livia)

Generalist carnivores can be effective biodiversity samplers of terrestrial vertebrates

Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants

Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry

A body map of somatic mutagenesis in morphologically normal human tissues

In-depth assessment of the PAM compatibility and editing activities of Cas9 variants

Global detection of DNA repair outcomes induced by CRISPR-Cas9

m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome

A widely diverged locus among Heliconius butterflies may be linked to locomotor adaptation

Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics

Genomic and transcriptomic profiling of hepatoid adenocarcinoma of the stomach